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GLP-1 dose chart: Wegovy, Ozempic, Zepbound and Mounjaro
Pick your medicine to see how its FDA label steps the weekly dose up, the maintenance doses, and what the label says about a missed dose.
Your doctor sets your dose, and it can differ from this chart for good reasons. Do not change your dose without talking to them.
Wegovy (semaglutide) dose chart
Once a week, injected under the skin. Approved for weight loss, lowering heart risk, and a kind of fatty liver disease (MASH).
| Weekly dose | When |
|---|---|
| 0.25 mg | Weeks 1 to 4 (starting dose) |
| 0.5 mg | Weeks 5 to 8 |
| 1 mg | Weeks 9 to 12 |
| 1.7 mg | Weeks 13 to 16 |
| 2.4 mg | Week 17 on (usual maintenance dose) |
| 7.2 mg | Adults taking it for weight loss, if the doctor raises it, after at least 4 weeks on 2.4 mg (highest dose) |
Maintenance dose
The usual maintenance dose is 2.4 mg once a week, and 1.7 mg is the other option (for MASH, only if 2.4 mg is hard to tolerate). For weight loss in adults who have taken 2.4 mg for at least 4 weeks, a doctor may raise the dose as high as 7.2 mg once a week. If a step is hard to tolerate, the label lets a doctor wait 4 more weeks before the next one.
If a dose is missed, the label says
If one dose is missed and the next is more than 2 days away, take it as soon as possible. If the next is less than 2 days away, skip it and take the next dose on the usual day. If 2 or more doses in a row are missed, the label says to restart at a lower dose, so talk to your doctor before the next one.
Wegovy also comes as a daily tablet with its own schedule. This chart covers the weekly injection.
Source: Wegovy FDA prescribing information on DailyMed, revised June 2026.
Ozempic (semaglutide) dose chart
Once a week, injected under the skin. Approved for type 2 diabetes, including lowering heart and kidney risk in people who have it.
| Weekly dose | When |
|---|---|
| 0.25 mg | Weeks 1 to 4 (starting dose) |
| 0.5 mg | Week 5 on |
| 1 mg | If more blood sugar control is needed, or for kidney disease, after at least 4 weeks on 0.5 mg |
| 2 mg | If more blood sugar control is needed, after at least 4 weeks on 1 mg |
Maintenance dose
The maintenance dose is 0.5 mg, 1 mg or 2 mg once a week, depending on blood sugar. The highest dose is 2 mg. For people with type 2 diabetes and chronic kidney disease, the label’s maintenance dose is 1 mg.
If a dose is missed, the label says
Take the missed dose as soon as possible within 5 days. If more than 5 days have passed, skip it and take the next dose on the usual day. The dose day can move, as long as doses are at least 2 days apart.
Ozempic also comes as a daily tablet with its own label. This chart covers the weekly injection.
Source: Ozempic FDA prescribing information on DailyMed, revised June 2026.
Zepbound (tirzepatide) dose chart
Once a week, injected under the skin. Approved for weight loss and obstructive sleep apnea.
| Weekly dose | When |
|---|---|
| 2.5 mg | Weeks 1 to 4 (starting dose) |
| 5 mg | Week 5 on |
| 7.5 mg | If raised, after at least 4 weeks on 5 mg |
| 10 mg | If raised, after at least 4 weeks on 7.5 mg |
| 12.5 mg | If raised, after at least 4 weeks on 10 mg |
| 15 mg | If raised, after at least 4 weeks on 12.5 mg |
Maintenance dose
For weight loss, the maintenance dose is 5 mg, 10 mg or 15 mg once a week. For sleep apnea it is 10 mg or 15 mg. The highest dose is 15 mg. 2.5 mg is only a starting dose.
If a dose is missed, the label says
Take the missed dose as soon as possible within 4 days (96 hours). If more than 4 days have passed, skip it and take the next dose on the usual day. The dose day can move, as long as doses are at least 3 days apart.
Source: Zepbound FDA prescribing information on DailyMed, revised August 2026.
Mounjaro (tirzepatide) dose chart
Once a week, injected under the skin. Approved for type 2 diabetes in adults and children 10 and older, including lowering heart risk in adults who have it.
| Weekly dose | When |
|---|---|
| 2.5 mg | Week 1 on (starting dose) |
| 5 mg | If more blood sugar control is needed, after at least 4 weeks on 2.5 mg |
| 7.5 mg | If more blood sugar control is needed, after at least 4 weeks on 5 mg |
| 10 mg | If more blood sugar control is needed, after at least 4 weeks on 7.5 mg |
| 12.5 mg | Adults only. If more blood sugar control is needed, after at least 4 weeks on 10 mg |
| 15 mg | Adults only. If more blood sugar control is needed, after at least 4 weeks on 12.5 mg |
Maintenance dose
The dose goes up only if blood sugar needs more control. The highest dose is 15 mg once a week for adults, and 10 mg for children 10 and older.
If a dose is missed, the label says
Take the missed dose as soon as possible within 4 days (96 hours). If more than 4 days have passed, skip it and take the next dose on the usual day. The dose day can move, as long as doses are at least 3 days apart.
Source: Mounjaro FDA prescribing information on DailyMed, revised August 2026.
This chart covers the brand-name medicines as their FDA labels describe them. For an emergency, call 911.